For regenerative medicine research,
there are many challenges.
- Obtain
enough
number of cells. - Assure
medical-grade
safety - Maintain
the potential
of therapeutic
cells
SCAPOVA™ PVA Microcarriers
can solve these problems!
3 reasons you choose
SCAPOVA™
1. Good cell proliferation rate
SCAPOVA™ can be applied
to cultivate therapeutic cells
such as MSCs.
Human cells cultured on various
microcarriers for 7days.
The proliferation rate vs.
initial cell number was estimated.
SCAPOVA™ showed higher cell proliferation capability than competitors’.
We have demonstrated 100l scale culture.
2. Quality management in accordance with medical standards
SCAPOVA™ is made from Kuraray’s PVA(※). We conduct strict quality management.
And there is extremely low risk of contamination.
(※)Polyvinyl Alcohol
SCAPOVA™ is not broken by collision during agitation. Because PVA material has excellent elasticity.
※This animation shows compression test of SCAPOVA™ (Red arrow)
| Safety test | Result |
|---|---|
| Endotoxin | ＜0.01EU/cm2 |
| Sterilization | SAL 10-6 (by gamma irradiation) |
| Cytotoxicity Genotoxicity Systemic acute toxicity Implantation test |
Negative (Tested in accordance with ISO 10993.) |
| Leachable Extractable |
Tested in accordance with BPOG guideline. |
For more information, please contact us.
3. Ease of handling
SCAPOVA™ CL is “Ready to use.” No need for sterilization and cleaning before use. It swells quickly in PBS or culture medium.
Swollen particles are highly transparent. Therefore, cells can be easily observed with a phase contrast microscope.
Particles swell quickly in medium or PBS.
Cells can be easily observed with a phase contrast microscope.
Product list
・SCAPOVA™ CL
Clinical grade collagen is coated on the particle surface. Endotoxin and virus in the collagen have been reduced or inactivated.
・SCAPOVA™ AS
The particle surface is special treated and activated. By activation, any cell adhesion molecules can be coated. In addition, it is an animal-free product containing no animal-derived materials.
Important Notice: For Research Use Only (RUO)
SCAPOVA™ PVA Microcarriers (the “Material”) are “For Research Use Only” and are not intended for use for any clinical or diagnostic purposes.
Users are solely responsible for the determination of the safety, efficacy, lawfulness and technical suitability of the Material for use in users’ products.
