Kuraray's Microcarriers

For regenerative medicine,
there are many challenges.

It is hard to
obtain enough
number of cells.
It is hard to
assure
medical-grade
safety
It is hard to
maintain the
potential of
therapeutic cell

SCAPOVA™ PVA Microcarriers
can solve these problems!

3 reasons you choose
SCAPOVA™

1. Good cell proliferation rate

SCAPOVA™ can be applied
to cultivate therapeutic cells
like MSCs.

Human cells cultured on each
microcarriers for 7days.
The proliferation rate vs.
initial cell number was estimated.

SCAPOVA™ has higher cell proliferation capability than competitors.

We have demonstrated 100l scale culture.

2. Quality management in accordance with medical standards

SCAPOVA™ is made from Kuraray’s PVA(※). We conduct strict quality management. And there is There is extremely low risk of contamination due to the material features.

(※)Polyvinyl Alcohol

SCAPOVA™ is not broken by collision during agitation. Because PVA material has excellent elasticity.

※This animation shows compression test of SCAPOVA™ (Red arrow)

Safety test	Result
Endotoxin	＜0.01EU/cm2
Sterilization	SAL 10-6 (by gamma irradiation)
Cytotoxicity Genotoxicity Systemic acute toxicity Implantation test	Negative (Tested in accordance with ISO 10993.)
Leachable Extractable	Tested in accordance with BPOG guideline.

For more information, please contact us.

3. Ease of handling

The use of SCAPOVA™ is easy. It is “Ready to use”. No need for sterilization and cleaning before using. It swells quickly in PBS or medium.
Swollen particle is highly transparency. Therefore, cells can be easily observed with a phase contrast microscope.